Biographical Sketch:
B.S. chemistry, Nanjing University China 1995 Ph.D. chemistry, Nanjing University China 2000
Interests:
My research interest is focused on the investigation of biological phenomena using microscopic and spectroscopic methods. Current projects target to quantify the antigen-antibody interaction, bacterial adhesion with atomic force microscope (AFM) and to develop a new AFM imaging method for biological samples, affinity mapping, based on the accurate quantification of adhesion force. We use various conjugation chemistry reactions to functionalize the AFM probes and abiotic substrates with live bacterial cells, viruses or proteins. Microarray of live bacterial cells and viruses can be constructed by using a combination of surface chemistry and affinity binding. Other research includes the study of surface chemistry using XPS, SEM and ToF-SIMS etc.
Selected Publications:
1. M. H. Schweitzer, Z.Y. Suo, R. Avci, J.M. Asara, M.A. Allen, F.T. Arce, J.R. Horner, “Analyses of Soft Tissue from Tyrannosaurus rex Suggest the Presence of Protein”, Science, 2007, 316(5822), 277-280. 2. Z.Y. Suo, X.Y. Yang, R. Avci, L. Kellerman, D.W. Pascual, M. Fries and A. Steele, “HEPES-Stabilized Encapsulation of Salmonella typhimurium”, Langmuir, 2007, 23(3), 1365-74. 3. X.H.Yang, B.J. Hinnebusch, T. Trunkle, C.M. Bosio, Z.Y. Suo, M. Tighe, A. Harmsen, T. Becker, K. Crist, N. Walters, R. Avci, D.W. Pascual, “Oral Vaccination With Salmonella Simultaneously Expressing Yersinia pestis F1 and V Antigens Protects Against Bubonic and Pneumonic Plague”, J. Immunol., 2007, 178(2), 1059-67. 4. Z.Y. Suo, F.T. Arce, R. Avci, K. Thieltges, B.D. Spangler, “Dendritic Structures of Poly(Ethylene Glycol) on Silicon Nitride and Gold Surfaces”, Langmuir, 2006, 22, 3844-50. 5. Z.Y. Suo, M. Drobizhev, C.W. Spangler, N. Christensson, A. Rebane, “New fluorophores based on trifluorenylamine with very large intrinsic three-photon absorption cross-sections”, Org. Lett., (2005), 7, 4807-10.
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